International Science Community Association International Research Journal of Biological Sciences 14 4 2025 11 10 Impact of Inclusion of Artificial Intelligence in Class 12 Biology Education : A Review 30 31 EN Khyade Vitthalrao Bhimasha 1 Department of Zoology, Sharadabai Pawar Mahila Arts, Commerce and Science College, Shardanagar Tal. Baramati Dist. Pune – 413115, India Khanapure Nikhil Pandit 2 Department of Chemistry, Punyashlok Ahilyadevi Holkar Solapur University, Solapur, Maharashtra-413 255, India . Shilpa 1 Department of Zoology, SSJDWSSS GPG College Ranikhet–263645, Uttarakhand, India Pandey Deepa 2 Department of Zoology, SSJDWSSS GPG College Ranikhet–263645, Uttarakhand, India Kumar Shankar 3 Department of Mathematics, SSJDWSSS GPG College Ranikhet–263645, Uttarakhand, India Gupta Pragati Kumari 1 Department of Zoology, Maharani Janki Kunwar College, Bettiah, West Champaran, Bihar-845438, India . Hafizurrahman 2 Department of Zoology, Maharani Janki Kunwar College, Bettiah, West Champaran, Bihar-845438, India Khan Saba 1 Department of Zoology, Maharshi Dayanand Saraswati University, Ajmer, Rajasthan, India and Department of Environmental Science (Centre for Excellence), Maharshi Dayanand Saraswati University, Ajmer, Rajasthan, India Singh Muskan 2 Department of Zoology, Maharshi Dayanand Saraswati University, Ajmer, Rajasthan, India and Department of Environmental Science (Centre for Excellence), Maharshi Dayanand Saraswati University, Ajmer, Rajasthan, India Yadav Divaker 3 Department of Zoology, Samrat Prithviraj Chouhan Government College, Ajmer, Rajasthan, India Chandra Subhash 4 Department of Zoology, Maharshi Dayanand Saraswati University, Ajmer, Rajasthan, India Dutta Subroto 5 Department of Environmental Science (Centre for Excellence), Maharshi Dayanand Saraswati University, Ajmer, Rajasthan, India L. Wadhwani 1 PM Shri Kendriya Vidhyalaya No. 2, Neemuch, Village Hingoria, Neemuch, Madhya Pradesh, India B. Asnani 2 Junagadh Agricultural University, Junagadh, Gujarat, India > Short Review Paper 2025 8 10 2025 11 10 The integration of Artificial Intelligence (AI) into secondary education is revolutionizing how complex subjects like Class 12 Biology are taught and learned. Biology education at this level encompasses challenging topics such as genetics, molecular biology, ecology, human physiology, and biotechnology, which demand deep conceptual understanding and critical thinking skills. AI applications—ranging from adaptive learning platforms and intelligent tutoring systems to immersive virtual laboratories and real-time automated assessments—are transforming traditional pedagogical methods by personalizing the learning experience, enhancing student engagement, and providing interactive, visual simulations of intricate biological processes. This paper presents a comprehensive review of the current AI technologies applied in Class 12 Biology classrooms worldwide, emphasizing their pedagogical value, effectiveness in improving comprehension, and role in preparing students for competitive exams and future scientific studies. The review synthesizes empirical research, case studies, and education policy frameworks such as India’s NEP 2020, highlighting AI’s potential to support diverse learning styles and overcome conventional limitations like scarce laboratory resources and time constraints. Furthermore, the paper discusses challenges in infrastructure, teacher training, data privacy, and ensuring a balance between AI-driven virtual experiments and hands-on learning. It advocates for ethically mindful, well-supported implementation of AI tools to maximize benefits while addressing equity issues. Ultimately, this investigation underscores Artificial Intelligence as a promising catalyst for enhancing quality, inclusivity, and effectiveness in senior secondary biology education, shaping a new paradigm aligned with the demands of 21st-century science education and career pathways. Copyright@ International Science Community Association