International Science Community Association International Research Journal of Biological Sciences 14 2 2025 05 10 Reasons led to reconsideration of botanicals as stored grain insect pest control agents 46 61 EN D. Doshita 1 Department of PG studies in Biotechnology, Nrupathunga University, NT road, Bangalore, India Khanum Saniya 2 Department of PG studies in Biotechnology, Nrupathunga University, NT road, Bangalore, India H. Anusha 3 Department of PG studies in Biotechnology, Nrupathunga University, NT road, Bangalore, India Khabade Sarina P. 4 Department of PG studies in Biotechnology, Nrupathunga University, NT road, Bangalore, India A. Geeta Rautela 1 Department of Botany, Aligarh Muslim University, Aligarh, Uttar Pradesh, India B. Rose Rizvi 2 Department of Botany, Aligarh Muslim University, Aligarh, Uttar Pradesh, India Samantaray Debajani 1 Plant Pathology and Microbiology Division, Regional Plant Resource Centre, Bhubaneswar, Odisha, India Mishra Atmaja Elina 2 Plant Pathology and Microbiology Division, Regional Plant Resource Centre, Bhubaneswar, Odisha, India Panda Subhransu 3 Siksha ‘O’ Anusandhan University, Bhubaneswar, Odisha, India Mohapatra Himadri Das 4 Siksha ‘O’ Anusandhan University, Bhubaneswar, Odisha, India Gupta Nibha 5 Plant Pathology and Microbiology Division, Regional Plant Resource Centre, Bhubaneswar, Odisha, India Sardar Shatavisa 1 Post Graduate Department of Zoology, Barasat Govt. College; 10, K.N.C. Road, Barasat, 24 Pgs North, Kolkata-700124, West Bengal, India Paul Sneha 2 Post Graduate Department of Zoology, Barasat Govt. College; 10, K.N.C. Road, Barasat, 24 Pgs North, Kolkata-700124, West Bengal, India Ghosh Jayati 3 Post Graduate Department of Zoology, Barasat Govt. College; 10, K.N.C. Road, Barasat, 24 Pgs North, Kolkata-700124, West Bengal, India Sarkar Sounak 1 MATS School of Sciences, MATS University, Raipur, Chhattisgarh, India Saraf Ashish 2 MATS School of Sciences, MATS University, Raipur, Chhattisgarh, India Dutta Joystu 3 Department of Environmental Science, Sant Gahira Guru Vishwavidyalaya Sarguja, Ambikapur, Chhattisgarh, India Lingampally Vasudha 1 Department of Zoology, Nizam College, Osmania University, Hyderabad, Telangana, India Solanki V.R. 2 Department of Zoology, University College of Science, Saifabad, Osmania University, Hyderabad, Telangana, India Raja S. Sabita 3 Department of Zoology, Nizam College, Osmania University, Hyderabad, Telangana, India > Review Paper 2024 11 10 2025 05 10 Ensuring the safety of food grains poses a significant and pressing challenge for grain handling organizations and experts in stored product entomology worldwide. Insects are universally recognised as the primary adversaries of stored grains, as they not only cause direct damage but also create an environment conducive to secondary infestations, primarily by fungal pathogens. Synthetic insecticides and fumigants have demonstrated higher efficacy in managing insect pests that affect stored grains. However, their widespread and indiscriminate use over many years, aimed at reducing post-harvest losses and preserving grain quality, has resulted in several adverse outcomes. These include the development of genetic resistance in pest species, lingering residues in stored grains, safety hazards during handling, pollution of storage environments, health concerns for humans, and detrimental impacts on the environment, thereby jeopardising the sustainability of ecosystems. These undesirable consequences have driven researchers to seek safer, efficient, and nontoxic grain protectants. Natural products derived from plants are increasingly gaining recognition as promising bio rational substitutes for synthetic insecticides in the control of postharvest insect pests. There has been a growing interest in various regions across the globe in investigating botanicals as a new approach to safeguarding grains. This review primarily focuses on the reasons that have sparked renewed scientific curiosity in utilising botanicals as stored grain insect pest control agents. It explores botanicals as an ecofriendly alternative to synthetic insecticides for stored grain insect pest management and provides an overview on the use of botanicals as stored grain insect pest control agents. This review also summarises the obstacles, constraints linked to the commercialization of botanicals as grain protectants. Copyright@ International Science Community Association