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Establishing correlations between different spindle and rpm for viscosity determination

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Author Affiliations

  • 1School of Pharmacy, Graphic Era Hill University, Dehradun, Uttarakhand, India
  • 2School of Pharmacy, Graphic Era Hill University, Dehradun, Uttarakhand, India
  • 3School of Pharmacy, Graphic Era Hill University, Dehradun, Uttarakhand, India
  • 4School of Pharmacy, Graphic Era Hill University, Dehradun, Uttarakhand, India

Res. J. of Pharmaceutical Sci., Volume 12, Issue (2), Pages 1-3, December,30 (2023)

Abstract

A non-Newtonian fluid is one that does not obey Newton’s law of viscosity. Determination of viscosity of pharmaceutical formulation like cream, paste, gel, lotion, highly viscous formulation is very important evaluation parameter. Ostwald’s viscometer could not be used for those liquids or material which shows non Newtonian flow. Viscosity of these material can be determine by Rotational viscometer. The aim of this study was to check the viscosity with different spindle no. and rpm and check their correlation. In study viscous glycerine and different spindle no 2, 3 and 4 were used. Results of viscosity in mPa.s were found to be 1392±8 (6 rpm), 978±4 (12 rpm), 760±9 (30 rpm), 539±6 (60 rpm) for spindle II, 3767±13 (6 rpm), 2332±18 (12 rpm), 1445±13 (30 rpm), 900±14 (60 rpm) for spindle III, and 17210±13 (6 rpm), 9659±19 (12 rpm), 4833±14 (30 rpm), 4080±12 (60 rpm) for spindle IV. A result shown that viscosity is also not only depends on type of spindle no. which is used for study but also rpm of spindle. So selection spindle no and rpm are crucial step during viscosity study.

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